Case

A 24-year-old woman with cystic fibrosis asks if she should take methylsulfonylmethane (MSM) to build her strength and energy. She wants to know if there are any known adverse effects from MSM.

Answer B is correct.

Many of the alleged benefits of MSM have been extrapolated from studies on dimethylsulfoxide (DMSO), which is structurally related but has distinct chemical behavior. MSM exhibits a potent ability to alkylate DNA, and it consistently induces lethal mutations in the offspring of treated mice. It has no known effect on energy, stamina, strength or pain.

Clinical reference texts on dietary supplements do not always contain complete and current information about toxicity, side effects and potential interactions. The most accurate information can be obtained from a poison control center or a pharmacist or other medical professional with expertise in herbs and dietary supplements.

FOR MORE INFORMATION
Our MSM page has links to information about MSM on other websites.

For information about herb/dietary supplement toxicity, go to:

Massachusetts Poison Control System - see "Publications" for toxicology reviews of Ephedra and St. John's Wort: http://www.mapoison.org

National Capital Poison Center's "Herbal Pearls":
http://www.poison.org/herbalpearls.htm

MedWatch, the FDA medical products reporting program:
http://www.fda.gov/medwatch

ABC's of Herbal Medicine | Herbs | Dietary Supplements | Vitamins & Minerals
Pediatric Conditions | In-depth Monographs | Clinician Information Summaries
Patient Fact Sheets | Articles by LHTF Members
Interactions & Toxicity Information | Resources & Links
| About the LHTF | How to Support the LHTF | Educational Opportunity!

Last Updated: August 29, 2001
Copyright © 2003 LHTF Disclaimer